Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons

Decreased rRNA synthesis and nucleolar disruption, known as nucleolar stress, are primary signs of cellular stress associated with aging and neurodegenerative disorders. Silencing of rDNA occurs during early stages of Alzheimer's disease (AD) and may play a role in dementia. Moreover, aberrant...

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Detalles Bibliográficos
Autores principales: Kiryk, Anna, Sowodniok, Katharina, Kreiner, Grzegorz, Rodriguez-Parkitna, Jan, Sönmez, Aynur, Górkiewicz, Tomasz, Bierhoff, Holger, Wawrzyniak, Marcin, Janusz, Artur K., Liss, Birgit, Konopka, Witold, Schütz, Günther, Kaczmarek, Leszek, Parlato, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823236/
https://www.ncbi.nlm.nih.gov/pubmed/24273493
http://dx.doi.org/10.3389/fncel.2013.00207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823236/
https://www.ncbi.nlm.nih.gov/pubmed/24273493
http://dx.doi.org/10.3389/fncel.2013.00207

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