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Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes

Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process. Since the hematogenous phase of tumour dissemination is the rate-limiting step in the metastatic process, we...

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Detalles Bibliográficos
Autores principales: Jones, Jon, Berkhoff, Stefan, Weich, Eva, Engl, Tobias, Wedel, Steffen, Relja, Borna, Jonas, Dietger, ABlaheta, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823260/
https://www.ncbi.nlm.nih.gov/pubmed/17760843
http://dx.doi.org/10.1111/j.1582-4934.2007.00071.x