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TNF-α-mediated signal transduction pathway is a major determinant of apoptosis in dilated cardiomyopathy

Although J2N-k strain of cardiomyopathic hamsters is an excellent model of dilated cardiomyopathy, the presence and mechanisms of apoptosis in the hearts of these genetically modified animals have not been investigated. This study examined the hypothesis that cardiac dysfunction and apoptosis in the...

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Detalles Bibliográficos
Autores principales: Das, Samarjit, Babick, Andrea P, Xu, Yan-Jun, Takeda, Nobuakira, Rodriguez-Levya, Delfin, Dhalla, Naranjan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823280/
https://www.ncbi.nlm.nih.gov/pubmed/19754666
http://dx.doi.org/10.1111/j.1582-4934.2009.00904.x