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Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells

In recent years, the use of anthraquinone laxatives, in particular senna, has been associated with damage to the intestinal epithelial layer and an increased risk of developing colorectal cancer. In this study, we evaluated the cytotoxicity of rhein, the active metabolite of senna, on human colon ad...

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Detalles Bibliográficos
Autores principales: Aviello, Gabriella, Rowland, Ian, Gill, Christopher I, Acquaviva, Angela Maria, Capasso, Francesco, McCann, Mark, Capasso, Raffaele, Izzo, Angelo A, Borrelli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823282/
https://www.ncbi.nlm.nih.gov/pubmed/19538468
http://dx.doi.org/10.1111/j.1582-4934.2009.00815.x