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Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells
In recent years, the use of anthraquinone laxatives, in particular senna, has been associated with damage to the intestinal epithelial layer and an increased risk of developing colorectal cancer. In this study, we evaluated the cytotoxicity of rhein, the active metabolite of senna, on human colon ad...
Autores principales: | Aviello, Gabriella, Rowland, Ian, Gill, Christopher I, Acquaviva, Angela Maria, Capasso, Francesco, McCann, Mark, Capasso, Raffaele, Izzo, Angelo A, Borrelli, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823282/ https://www.ncbi.nlm.nih.gov/pubmed/19538468 http://dx.doi.org/10.1111/j.1582-4934.2009.00815.x |
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