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α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway

Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality. Although several reports have implicated mitochondrial dysfunction in cardiovascular disease and chronic kidney disease, little is known about the potential role...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsoo, Kim, Han-Jong, Lee, Kyunghee, Kim, Jin-Man, Kim, Hee Sun, Kim, Jae-Ryong, Ha, Chae-Myeong, Choi, Young-Keun, Lee, Sun Joo, Kim, Joon-Young, Harris, Robert A, Jeong, Daewon, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823291/
https://www.ncbi.nlm.nih.gov/pubmed/21362131
http://dx.doi.org/10.1111/j.1582-4934.2011.01294.x