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STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy

Previous studies have shown that the transcription factor signal transducer and activator of transcription 1 (STAT1) activation is increased in primary cardiac myocytes exposed to simulated ischaemia/reperfusion injury. This promotes apoptotic cell death by enhancing the expression of pro-apoptotic...

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Detalles Bibliográficos
Autores principales: McCormick, J, Suleman, N, Scarabelli, TM, Knight, RA, Latchman, DS, Stephanou, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823301/
https://www.ncbi.nlm.nih.gov/pubmed/21447043
http://dx.doi.org/10.1111/j.1582-4934.2011.01323.x