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Atorvastatin activates heme oxygenase-1 at the stress response elements

Statins are known to inhibit growth of a number of cancer cells, but their mechanism of action is not well established. In this study, human prostate adenocarcinoma PC-3 and breast adenocarcinoma MCF-7 cell lines were used as models to investigate the mechanism of action of atorvastatin, one of the...

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Detalles Bibliográficos
Autores principales: Kwok, Simon CM, Samuel, Solomon P, Handal, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823302/
https://www.ncbi.nlm.nih.gov/pubmed/21447045
http://dx.doi.org/10.1111/j.1582-4934.2011.01324.x