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Papuamine causes autophagy following the reduction of cell survival through mitochondrial damage and JNK activation in MCF-7 human breast cancer cells

We previously reported that extracts of an Indonesian marine sponge Haliclona sp. showed potent cytotoxicity and the induction of apoptosis against human solid cancer cell lines. In this study, we examine the cytotoxic mechanism of the major chemical compound, papuamine, on MCF-7 human breast cancer...

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Detalles Bibliográficos
Autores principales: KANNO, SYU-ICHI, YOMOGIDA, SHIN, TOMIZAWA, AYAKO, YAMAZAKI, HIROYUKI, UKAI, KAZUYO, MANGINDAAN, REMY E.P., NAMIKOSHI, MICHIO, ISHIKAWA, MASAAKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823348/
https://www.ncbi.nlm.nih.gov/pubmed/24026338
http://dx.doi.org/10.3892/ijo.2013.2093