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SIRT3 regulates cell proliferation and apoptosis related to energy metabolism in non-small cell lung cancer cells through deacetylation of NMNAT2

Lung cancer is the leading cause of death worldwide and associated with dismal prognoses. As a major mitochondrial deacetylase, SIRT3 regulates the activity of enzymes to coordinate global shifts in cellular metabolism and has important implications for tumor growth. Its role as a tumor suppressor o...

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Detalles Bibliográficos
Autores principales: LI, HONGQI, FENG, ZHIQIANG, WU, WEIZHANG, LI, JING, ZHANG, JINQIAN, XIA, TINGYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823398/
https://www.ncbi.nlm.nih.gov/pubmed/24042441
http://dx.doi.org/10.3892/ijo.2013.2103