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Re-expression of alpha skeletal actin as a marker for dedifferentiation in cardiac pathologies
Differentiation of foetal cardiomyocytes is accompanied by sequential actin isoform expression, i.e. down-regulation of the ‘embryonic’ alpha smooth muscle actin, followed by an up-regulation of alpha skeletal actin (αSKA) and a final predominant expression of alpha cardiac actin (αCA). Our objectiv...
Autores principales: | Driesen, Ronald B, Verheyen, Fons K, Debie, Wiel, Blaauw, Erik, Babiker, Fawzi A, Cornelussen, Richard NM, Ausma, Jannie, Lenders, Marie-Hélène, Borgers, Marcel, Chaponnier, Christine, Ramaekers, Frans C S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823406/ https://www.ncbi.nlm.nih.gov/pubmed/19538254 http://dx.doi.org/10.1111/j.1582-4934.2008.00523.x |
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