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Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway

Oxidative stress plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. Because crocetin represses oxidative stress in vitro and in vivo, we have suggested that crocetin would repress cardiac hypertrophy by targeting oxidative stress-dependent signalling. We...

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Detalles Bibliográficos
Autores principales: Cai, Jun, Yi, Fang-Fang, Bian, Zhou-Yan, Shen, Di-Fei, Yang, Long, Yan, Ling, Tang, Qi-Zhu, Yang, Xin-Chun, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823407/
https://www.ncbi.nlm.nih.gov/pubmed/19413885
http://dx.doi.org/10.1111/j.1582-4934.2008.00620.x