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Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway
Oxidative stress plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. Because crocetin represses oxidative stress in vitro and in vivo, we have suggested that crocetin would repress cardiac hypertrophy by targeting oxidative stress-dependent signalling. We...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823407/ https://www.ncbi.nlm.nih.gov/pubmed/19413885 http://dx.doi.org/10.1111/j.1582-4934.2008.00620.x |