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AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR

Angiogenesis plays an important role in neoplastic transformation and progression as well as in the metastasis process of most human cancers. Herein, we identified AL3810 as a novel and orally bioavailable small molecular inhibitor with potent inhibitory activity against multiple tyrosine kinases in...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanfeng, Chen, Yi, Tong, Linjiang, Xie, Hua, Wen, Weiwei, Zhang, Jie, Xi, Yong, Shen, Yanyan, Geng, Meiyu, Wang, Yuanyuan, Jiang, Hualiang, Luo, Cheng, Lin, Liping, Ding, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823425/
https://www.ncbi.nlm.nih.gov/pubmed/22304225
http://dx.doi.org/10.1111/j.1582-4934.2012.01541.x