Elastin overexpression by cell-based gene therapy preserves matrix and prevents cardiac dilation

After a myocardial infarction, thinning and expansion of the fibrotic scar contribute to progressive heart failure. The loss of elastin is a major contributor to adverse extracellular matrix remodelling of the infarcted heart, and restoration of the elastic properties of the infarct region can preve...

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Detalles Bibliográficos
Autores principales: Li, Shu-Hong, Sun, Zhuo, Guo, Lily, Han, Mihan, Wood, Michael F G, Ghosh, Nirmalya, Alex Vitkin, I, Weisel, Richard D, Li, Ren-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823437/
https://www.ncbi.nlm.nih.gov/pubmed/22435995
http://dx.doi.org/10.1111/j.1582-4934.2012.01560.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823437/
https://www.ncbi.nlm.nih.gov/pubmed/22435995
http://dx.doi.org/10.1111/j.1582-4934.2012.01560.x

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