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Elastin overexpression by cell-based gene therapy preserves matrix and prevents cardiac dilation
After a myocardial infarction, thinning and expansion of the fibrotic scar contribute to progressive heart failure. The loss of elastin is a major contributor to adverse extracellular matrix remodelling of the infarcted heart, and restoration of the elastic properties of the infarct region can preve...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823437/ https://www.ncbi.nlm.nih.gov/pubmed/22435995 http://dx.doi.org/10.1111/j.1582-4934.2012.01560.x |