Transplantation of novel human GDF5-expressing CHO cells is neuroprotective in models of Parkinson's disease

Growth/differentiation factor 5 (GDF5) is a neurotrophic factor that promotes the survival of midbrain dopaminergic neurons in vitro and in vivo and as such is potentially useful in the treatment of Parkinson's disease (PD). This study shows that a continuous supply of GDF5, produced by transpl...

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Detalles Bibliográficos
Autores principales: Costello, Daniel J, O'Keeffe, Gerard W, Hurley, Fiona M, Sullivan, Aideen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823439/
https://www.ncbi.nlm.nih.gov/pubmed/22436046
http://dx.doi.org/10.1111/j.1582-4934.2012.01562.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823439/
https://www.ncbi.nlm.nih.gov/pubmed/22436046
http://dx.doi.org/10.1111/j.1582-4934.2012.01562.x

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