Deletion of angiotensin II type 1 receptor gene or scavenge of superoxide prevents chronic alcohol-induced aortic damage and remodelling

To investigate whether chronic alcohol consumption induces vascular injury via angiotensin II (Ang II) type 1 (AT1) receptor-dependent superoxide generation, male transgenic mice with knockout of AT1 gene (AT1-KO) and age-matched wild-type (WT) C57BL/6 mice were pair-fed a modified Lieber-DeCarli al...

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Detalles Bibliográficos
Autores principales: Bai, Yang, Tan, Yi, Wang, Bo, Miao, Xiao, Chen, Qiang, Zheng, Yang, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823445/
https://www.ncbi.nlm.nih.gov/pubmed/22435601
http://dx.doi.org/10.1111/j.1582-4934.2012.01569.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823445/
https://www.ncbi.nlm.nih.gov/pubmed/22435601
http://dx.doi.org/10.1111/j.1582-4934.2012.01569.x

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