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Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells

Garlic organosulphur compounds have been successfully used as redox anti-proliferative agents. In this work, we dissect the effects of diallyl disulphide (DADS) focusing on the events upstream of cell cycle arrest and apoptosis induced in neuroblastoma SH-SY5Y cells. We demonstrate that DADS is able...

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Detalles Bibliográficos
Autores principales: Aquilano, Katia, Vigilanza, Paola, Filomeni, Giuseppe, Rotilio, Giuseppe, Ciriolo, Maria R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823456/
https://www.ncbi.nlm.nih.gov/pubmed/19040422
http://dx.doi.org/10.1111/j.1582-4934.2008.00588.x