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Non-viral VEGF(165) gene therapy – magnetofection of acoustically active magnetic lipospheres (‘magnetobubbles’) increases tissue survival in an oversized skin flap model

Adenoviral transduction of the VEGF gene in an oversized skin flap increases flap survival and perfusion. In this study, we investigated the potential of magnetofection of magnetic lipospheres containing VEGF(165)-cDNA on survival and perfusion of ischemic skin flaps and evaluated the method with re...

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Detalles Bibliográficos
Autores principales: Holzbach, Thomas, Vlaskou, Dialekti, Neshkova, Iva, Konerding, Moritz A, Wörtler, Klaus, Mykhaylyk, Olga, Gänsbacher, Bernd, Machens, H-G, Plank, Christian, Giunta, Riccardo E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823458/
https://www.ncbi.nlm.nih.gov/pubmed/19040418
http://dx.doi.org/10.1111/j.1582-4934.2008.00592.x