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Calcineurin inhibition enhances motor neuron survival following injury

The immunosuppressive agents cyclosporin A (CsA) and FK-506 have previously been shown to exhibit neurotrophic and neuroprotective properties in vivo. Given that significant clinical expertise exists for both drugs, they represent an attractive starting point for treatment of acute neural injuries....

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Detalles Bibliográficos
Autores principales: Hui, Kelvin KW, Liadis, Nicole, Robertson, Jennifer, Kanungo, Anish, Henderson, Jeffrey T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823465/
https://www.ncbi.nlm.nih.gov/pubmed/19243469
http://dx.doi.org/10.1111/j.1582-4934.2009.00715.x