Characterization of Dextran Sodium Sulfate-Induced Inflammation and Colonic Tumorigenesis in Smad3 (−/−) Mice with Dysregulated TGFβ

There are few mouse models that adequately mimic large bowel cancer in humans or the gastrointestinal inflammation which frequently precedes it. Dextran sodium sulphate (DSS)-induces colitis in many animal models and has been used in combination with the carcinogen azoxymethane (AOM) to induce cance...

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Detalles Bibliográficos
Autores principales: Seamons, Audrey, Treuting, Piper M., Brabb, Thea, Maggio-Price, Lillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823566/
https://www.ncbi.nlm.nih.gov/pubmed/24244446
http://dx.doi.org/10.1371/journal.pone.0079182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823566/
https://www.ncbi.nlm.nih.gov/pubmed/24244446
http://dx.doi.org/10.1371/journal.pone.0079182

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