Cargando…
Activation of the B Cell Receptor Leads to Increased Membrane Proximity of the Igα Cytoplasmic Domain
Binding of antigen to the B cell receptor (BCR) induces conformational changes in BCR's cytoplasmic domains that are concomitant with phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs). Recently, reversible folding of the CD3ε and ξ chain ITAMs into the plasma membra...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823606/ https://www.ncbi.nlm.nih.gov/pubmed/24244439 http://dx.doi.org/10.1371/journal.pone.0079148 |