Divergent evolution of protein conformational dynamics in dihydrofolate reductase

Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the evolution of protein function, but little is known...

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Detalles Bibliográficos
Autores principales: Bhabha, Gira, Ekiert, Damian C., Jennewein, Madeleine, Zmasek, Christian M., Tuttle, Lisa M., Kroon, Gerard, Dyson, H. Jane, Godzik, Adam, Wilson, Ian A., Wright, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823643/
https://www.ncbi.nlm.nih.gov/pubmed/24077226
http://dx.doi.org/10.1038/nsmb.2676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823643/
https://www.ncbi.nlm.nih.gov/pubmed/24077226
http://dx.doi.org/10.1038/nsmb.2676

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