A Structure-Toxicity Study of Aß(42) Reveals a New Anti-Parallel Aggregation Pathway

Amyloid beta (Aβ) peptides produced by APP cleavage are central to the pathology of Alzheimer’s disease. Despite widespread interest in this issue, the relationship between the auto-assembly and toxicity of these peptides remains controversial. One intriguing feature stems from their capacity to for...

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Detalles Bibliográficos
Autores principales: Vignaud, Hélène, Bobo, Claude, Lascu, Ioan, Sörgjerd, Karin Margareta, Zako, Tamotsu, Maeda, Mizuo, Salin, Benedicte, Lecomte, Sophie, Cullin, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823702/
https://www.ncbi.nlm.nih.gov/pubmed/24244667
http://dx.doi.org/10.1371/journal.pone.0080262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823702/
https://www.ncbi.nlm.nih.gov/pubmed/24244667
http://dx.doi.org/10.1371/journal.pone.0080262

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