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A Structure-Toxicity Study of Aß(42) Reveals a New Anti-Parallel Aggregation Pathway
Amyloid beta (Aβ) peptides produced by APP cleavage are central to the pathology of Alzheimer’s disease. Despite widespread interest in this issue, the relationship between the auto-assembly and toxicity of these peptides remains controversial. One intriguing feature stems from their capacity to for...
Autores principales: | Vignaud, Hélène, Bobo, Claude, Lascu, Ioan, Sörgjerd, Karin Margareta, Zako, Tamotsu, Maeda, Mizuo, Salin, Benedicte, Lecomte, Sophie, Cullin, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823702/ https://www.ncbi.nlm.nih.gov/pubmed/24244667 http://dx.doi.org/10.1371/journal.pone.0080262 |
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