Misrepair of DNA double-strand breaks after exposure to heavy-ion beams causes a peak in the LET–RBE relationship with respect to cell killing in DT40 cells

To determine the radiobiological mechanisms underlying relative biological effectiveness (RBE) and the repair efficiencies of DNA double-strand breaks (DSBs) as a function of linear energy transfer (LET), we exposed cells of the chicken B-lymphocyte cell line DT40 and its DSB repair pathway-deficien...

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Detalles Bibliográficos
Autores principales: Aoki-Nakano, Mizuho, Furusawa, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823785/
https://www.ncbi.nlm.nih.gov/pubmed/23722078
http://dx.doi.org/10.1093/jrr/rrt064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823785/
https://www.ncbi.nlm.nih.gov/pubmed/23722078
http://dx.doi.org/10.1093/jrr/rrt064

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