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Misrepair of DNA double-strand breaks after exposure to heavy-ion beams causes a peak in the LET–RBE relationship with respect to cell killing in DT40 cells

To determine the radiobiological mechanisms underlying relative biological effectiveness (RBE) and the repair efficiencies of DNA double-strand breaks (DSBs) as a function of linear energy transfer (LET), we exposed cells of the chicken B-lymphocyte cell line DT40 and its DSB repair pathway-deficien...

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Detalles Bibliográficos
Autores principales:	Aoki-Nakano, Mizuho, Furusawa, Yoshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823785/ https://www.ncbi.nlm.nih.gov/pubmed/23722078 http://dx.doi.org/10.1093/jrr/rrt064

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