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Epitope Predictions Indicate the Presence of Two Distinct Types of Epitope-Antibody-Reactivities Determined by Epitope Profiling of Intravenous Immunoglobulins

Epitope-antibody-reactivities (EAR) of intravenous immunoglobulins (IVIGs) determined for 75,534 peptides by microarray analysis demonstrate that roughly 9% of peptides derived from 870 different human protein sequences react with antibodies present in IVIG. Computational prediction of linear B cell...

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Detalles Bibliográficos
Autores principales: Luštrek, Mitja, Lorenz, Peter, Kreutzer, Michael, Qian, Zilliang, Steinbeck, Felix, Wu, Di, Born, Nadine, Ziems, Bjoern, Hecker, Michael, Blank, Miri, Shoenfeld, Yehuda, Cao, Zhiwei, Glocker, Michael O., Li, Yixue, Fuellen, Georg, Thiesen, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823795/
https://www.ncbi.nlm.nih.gov/pubmed/24244326
http://dx.doi.org/10.1371/journal.pone.0078605