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Epitope Predictions Indicate the Presence of Two Distinct Types of Epitope-Antibody-Reactivities Determined by Epitope Profiling of Intravenous Immunoglobulins
Epitope-antibody-reactivities (EAR) of intravenous immunoglobulins (IVIGs) determined for 75,534 peptides by microarray analysis demonstrate that roughly 9% of peptides derived from 870 different human protein sequences react with antibodies present in IVIG. Computational prediction of linear B cell...
Autores principales: | Luštrek, Mitja, Lorenz, Peter, Kreutzer, Michael, Qian, Zilliang, Steinbeck, Felix, Wu, Di, Born, Nadine, Ziems, Bjoern, Hecker, Michael, Blank, Miri, Shoenfeld, Yehuda, Cao, Zhiwei, Glocker, Michael O., Li, Yixue, Fuellen, Georg, Thiesen, Hans-Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823795/ https://www.ncbi.nlm.nih.gov/pubmed/24244326 http://dx.doi.org/10.1371/journal.pone.0078605 |
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