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Simultaneous Expression of Displayed and Secreted Antibodies for Antibody Screen

The display of full-length antibody on the cell surface was achieved by fusing a transmembrane domain of the platelet-derived growth factor receptor (PDGFR) to the C-terminus of the heavy chain constant region. We also incorporated a furin cleavage site between the constant region and PDGFR transmem...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanping, Wang, Junjie, Zhou, Ivan, Lou, Haibo, Li, Chang-Zheng, Chen, Zhen-Rui, Zhang, Zhe-Huan, Liu, Shuwen, Wu, Shuguang, Tan, Wanlong, Jiang, Shibo, Zhou, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823846/
https://www.ncbi.nlm.nih.gov/pubmed/24244593
http://dx.doi.org/10.1371/journal.pone.0080005