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Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data
Computational inference of novel therapeutic values for existing drugs, i.e., drug repositioning, offers the great prospect for faster and low-risk drug development. Previous researches have indicated that chemical structures, target proteins, and side-effects could provide rich information in drug...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823875/ https://www.ncbi.nlm.nih.gov/pubmed/24244318 http://dx.doi.org/10.1371/journal.pone.0078518 |