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Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

Computational inference of novel therapeutic values for existing drugs, i.e., drug repositioning, offers the great prospect for faster and low-risk drug development. Previous researches have indicated that chemical structures, target proteins, and side-effects could provide rich information in drug...

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Detalles Bibliográficos
Autores principales: Wang, Yongcui, Chen, Shilong, Deng, Naiyang, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823875/
https://www.ncbi.nlm.nih.gov/pubmed/24244318
http://dx.doi.org/10.1371/journal.pone.0078518