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Genome-Wide Analysis of the Phosphoinositide Kinome from Two Ciliates Reveals Novel Evolutionary Links for Phosphoinositide Kinases in Eukaryotic Cells

BACKGROUND: The complexity of phosphoinositide signaling in higher eukaryotes is partly due to expansion of specific families and types of phosphoinositide kinases (PIKs) that can generate all phosphoinositides via multiple routes. This is particularly evident in the PI3Ks and PIPKs, and it is consi...

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Detalles Bibliográficos
Autores principales: Leondaritis, George, Siokos, John, Skaripa, Irini, Galanopoulou, Dia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823935/
https://www.ncbi.nlm.nih.gov/pubmed/24244373
http://dx.doi.org/10.1371/journal.pone.0078848