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Single Intraperitoneal Injection of Monocrotaline as a Novel Large Animal Model of Chronic Pulmonary Hypertension in Tibet Minipigs

OBJECTIVE: The purpose of this study was to establish an animal model of chronic pulmonary hypertension with a single-dose intraperitoneal injection of monocrotaline (MCT) in young Tibet minipigs, so as to enable both invasive and noninvasive measurements and hence facilitate future studies. METHODS...

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Detalles Bibliográficos
Autores principales: Zeng, Guang-qiao, Liu, Rong, Liao, Hai-xing, Zhang, Xin-feng, Qian, Yuan-xin, Liu, Bao-hua, Wu, Qing-hong, Zhao, Jin, Gu, Wei-wang, Li, Hong-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823945/
https://www.ncbi.nlm.nih.gov/pubmed/24244396
http://dx.doi.org/10.1371/journal.pone.0078965