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Disappearance of Hypoxic Pulmonary Vasoconstriction and O(2)-Sensitive Nonselective Cationic Current in Arterial Myocytes of Rats Under Ambient Hypoxia
Acute hypoxia induces contraction of pulmonary artery (PA) to protect ventilation/perfusion mismatch in lungs. As for the cellular mechanism of hypoxic pulmonary vasoconstriction (HPV), hypoxic inhibition of voltage-gated K(+) channel (Kv) in PA smooth muscle cell (PASMC) has been suggested. In addi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823961/ https://www.ncbi.nlm.nih.gov/pubmed/24227949 http://dx.doi.org/10.4196/kjpp.2013.17.5.463 |