Panobinostat Enhances Cytarabine and Daunorubicin Sensitivities in AML Cells through Suppressing the Expression of BRCA1, CHK1, and Rad51

Acute myeloid leukemia (AML) remains a challenging disease to treat and urgently requires new therapies to improve its treatment outcome. In this study, we investigated the molecular mechanisms underlying the cooperative antileukemic activities of panobinostat and cytarabine or daunorubicin (DNR) in...

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Detalles Bibliográficos
Autores principales: Xie, Chengzhi, Drenberg, Christina, Edwards, Holly, Caldwell, J. Timothy, Chen, Wei, Inaba, Hiroto, Xu, Xuelian, Buck, Steven A., Taub, Jeffrey W., Baker, Sharyn D., Ge, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823972/
https://www.ncbi.nlm.nih.gov/pubmed/24244429
http://dx.doi.org/10.1371/journal.pone.0079106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823972/
https://www.ncbi.nlm.nih.gov/pubmed/24244429
http://dx.doi.org/10.1371/journal.pone.0079106

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