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Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5

The serine/threonine protein phosphatase protein phosphatase 1 (PP1) is known to play an important role in learning and memory by mediating local and downstream aspects of synaptic signaling, but how PP1 activity is controlled in different forms of synaptic plasticity remains unknown. We find that s...

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Detalles Bibliográficos
Autores principales: Hou, Hailong, Sun, Lu, Siddoway, Benjamin A., Petralia, Ronald S., Yang, Hongtian, Gu, Hua, Nairn, Angus C., Xia, Houhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824016/
https://www.ncbi.nlm.nih.gov/pubmed/24189275
http://dx.doi.org/10.1083/jcb.201303035