Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture

Centrioles are evolutionarily conserved eukaryotic organelles composed of a protein scaffold surrounded by sets of microtubules organized with a 9-fold radial symmetry. CPAP, a centriolar protein essential for microtubule recruitment, features a C-terminal domain of unknown structure, the G-box. A m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hatzopoulos, Georgios N., Erat, Michèle C., Cutts, Erin, Rogala, Kacper B., Slater, Leanne M., Stansfeld, Philip J., Vakonakis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824074/
https://www.ncbi.nlm.nih.gov/pubmed/24076405
http://dx.doi.org/10.1016/j.str.2013.08.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824074/
https://www.ncbi.nlm.nih.gov/pubmed/24076405
http://dx.doi.org/10.1016/j.str.2013.08.019

Ejemplares similares