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Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats

Here, for the first time, we test a novel hypothesis that systemic treatment of stroke with exosomes derived from multipotent mesenchymal stromal cells (MSCs) promote neurovascular remodeling and functional recovery after stroke in rats. Adult male Wistar rats were subjected to 2 hours of middle cer...

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Detalles Bibliográficos
Autores principales: Xin, Hongqi, Li, Yi, Cui, Yisheng, Yang, James J, Zhang, Zheng Gang, Chopp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824189/
https://www.ncbi.nlm.nih.gov/pubmed/23963371
http://dx.doi.org/10.1038/jcbfm.2013.152