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Optimizing Surgical and Imatinib Therapy for the Treatment of Gastrointestinal Stromal Tumors

INTRODUCTION: The discovery of activating KIT and PDGFRα mutations in gastrointestinal stromal tumors (GISTs) represented a milestone as it allowed clinicians to use tyrosine kinase inhibitors, like imatinib, to treat this sarcoma. Although surgery remains the only potentially curative treatment, pa...

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Detalles Bibliográficos
Autores principales: Sicklick, Jason K., Lopez, Nicole E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824223/
https://www.ncbi.nlm.nih.gov/pubmed/23775094
http://dx.doi.org/10.1007/s11605-013-2243-0