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Beneficial and Detrimental Roles of NLRs in Carcinogenesis

Inflammation plays a critical role in tumorigenesis and can contribute to oncogenic mutations, tumor promotion, and angiogenesis. Tumor-promoting inflammation is driven by many factors including the presence of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. One major source of IL-1β a...

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Detalles Bibliográficos
Autores principales: Janowski, Ann M., Kolb, Ryan, Zhang, Weizhou, Sutterwala, Fayyaz S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824244/
https://www.ncbi.nlm.nih.gov/pubmed/24273542
http://dx.doi.org/10.3389/fimmu.2013.00370