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Hedgehog signal inhibitors suppress the invasion of human rhabdomyosarcoma cells

PURPOSE: In the treatment of rhabdomyosarcoma (RMS), invasion and metastasis remain the most critical determinants of resectability and survival. The objective of this study was to determine whether Hedgehog (Hh) signaling plays a role in the invasion of RMS. METHODS: Two kinds of specific Hh signal...

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Detalles Bibliográficos
Autores principales: Oue, Takaharu, Uehara, Shuichiro, Yamanaka, Hiroaki, Nomura, Motonari, Usui, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824305/
https://www.ncbi.nlm.nih.gov/pubmed/23989521
http://dx.doi.org/10.1007/s00383-013-3369-6