LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis

BACKGROUND: Genome-wide DNA hypomethylation plays an important role in genomic instability and carcinogenesis. DNA methylation in the long interspersed nucleotide element-1, L1 (LINE-1) repetitive element is a good indicator of the global DNA methylation level. In some types of human neoplasms, LINE...

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Detalles Bibliográficos
Autores principales: Shigaki, Hironobu, Baba, Yoshifumi, Watanabe, Masayuki, Murata, Asuka, Iwagami, Shiro, Miyake, Keisuke, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824342/
https://www.ncbi.nlm.nih.gov/pubmed/23179365
http://dx.doi.org/10.1007/s10120-012-0209-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824342/
https://www.ncbi.nlm.nih.gov/pubmed/23179365
http://dx.doi.org/10.1007/s10120-012-0209-7

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