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Rapamycin suppresses brain aging in senescence-accelerated OXYS rats

Cellular and organismal aging are driven in part by the MTOR (mechanistic target of rapamycin) pathway and rapamycin extends life span in C elegans, Drosophila and mice. Herein, we investigated effects of rapamycin on brain aging in OXYS rats. Previously we found, in OXYS rats, an early development...

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Detalles Bibliográficos
Autores principales: Kolosova, Nataliya G., Vitovtov, Anton O., Muraleva, Natalia A, Akulov, Andrey E., Stefanova, Natalia A., Blagosklonny, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824413/
https://www.ncbi.nlm.nih.gov/pubmed/23817674