Cargando…

DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity

Stability of proteins is largely controlled by post-translational covalent modifications. Among those, ubiquitylation plays a central role as it marks the proteins for proteasome-dependent degradation. Proteolytic activities of proteasomes are critical for execution of various cellular processes, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Moiseeva, Tatiana N., Bottrill, Andrew, Melino, Gerry, Barlev, Nickolai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824523/
https://www.ncbi.nlm.nih.gov/pubmed/23907514