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DNA damage-induced ubiquitylation of proteasome controls its proteolytic activity
Stability of proteins is largely controlled by post-translational covalent modifications. Among those, ubiquitylation plays a central role as it marks the proteins for proteasome-dependent degradation. Proteolytic activities of proteasomes are critical for execution of various cellular processes, in...
Autores principales: | Moiseeva, Tatiana N., Bottrill, Andrew, Melino, Gerry, Barlev, Nickolai A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824523/ https://www.ncbi.nlm.nih.gov/pubmed/23907514 |
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