Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway

Expansion of polyalanine tracts causes at least nine inherited human diseases. Among these, a polyalanine tract expansion in the poly (A)-binding protein nuclear 1 ((exp)PABPN1) causes oculopharyngeal muscular dystrophy (OPMD). So far, there is no treatment for OPMD patients. Developing drugs that e...

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Detalles Bibliográficos
Autores principales: Abu-Baker, A, Laganiere, J, Gaudet, R, Rochefort, D, Brais, B, Neri, C, Dion, P A, Rouleau, G A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824652/
https://www.ncbi.nlm.nih.gov/pubmed/24091664
http://dx.doi.org/10.1038/cddis.2013.342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824652/
https://www.ncbi.nlm.nih.gov/pubmed/24091664
http://dx.doi.org/10.1038/cddis.2013.342

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