Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110

A network of heat-shock proteins mediates cellular protein homeostasis, and has a fundamental role in preventing aggregation-associated neurodegenerative diseases. In a Drosophila model of polyglutamine (polyQ) disease, the HSP40 family protein, DNAJ-1, is a superior suppressor of toxicity caused by...

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Detalles Bibliográficos
Autores principales: Kuo, Y, Ren, S, Lao, U, Edgar, B A, Wang, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824661/
https://www.ncbi.nlm.nih.gov/pubmed/24091676
http://dx.doi.org/10.1038/cddis.2013.351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824661/
https://www.ncbi.nlm.nih.gov/pubmed/24091676
http://dx.doi.org/10.1038/cddis.2013.351

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