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Role of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity
The clinical use of the antineoplastic drug cisplatin is limited by its deleterious nephrotoxic side effect. Cisplatin-induced nephrotoxicity is associated with an increase in oxidative stress, leading ultimately to renal cell death and irreversible kidney dysfunction. Oxidative stress could be modi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824665/ https://www.ncbi.nlm.nih.gov/pubmed/24091660 http://dx.doi.org/10.1038/cddis.2013.355 |