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Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cells

Arginase, an arginine-degrading enzyme, has gained increased attention recently as a new experimental therapeutics for a variety of malignant solid cancers. In this study, we found that recombinant human arginase (rhArg) could induce remarkable growth inhibition, cell cycle arrest, and caspase-depen...

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Detalles Bibliográficos
Autores principales: Zeng, X, Li, Y, Fan, J, Zhao, H, Xian, Z, Sun, Y, Wang, Z, Wang, S, Zhang, G, Ju, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824669/
https://www.ncbi.nlm.nih.gov/pubmed/24113174
http://dx.doi.org/10.1038/cddis.2013.359