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A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance
The emergence of drug resistant tumours that are able to escape cell death pose a major problem in the treatment of cancers. Tumours develop resistance to DNA-damaging chemotherapeutic agents by acquiring the ability to repair their DNA. Combination therapies that induce DNA damage and disrupt the D...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824674/ https://www.ncbi.nlm.nih.gov/pubmed/24113180 http://dx.doi.org/10.1038/cddis.2013.365 |